Sentence examples for wfa 1 from inspiring English sources

WFA (1 µM) induced marked apoptosis in wild-type vimentin transfected cells in which vimentin degradation and caspase-3 activation were observed (Figure 4C).

Similarly, WFA (1 µM for 24 h) elicited a significantly higher apoptotic rate in vimentin-expressing carcinoma cells (P<0.05; Figure 7B).

To determine apoptosis in cells grown in suspension (Anoikis), 5×105 cells/ml SKLMS1 and NHDF cells were placed in 15 ml conical tubes with filter caps in a total volume of 8 ml complete DMEM/F12 media, and tubes were placed in a continuous rotator in a cell culture incubator with and without WFA (1 µM).

Higher dose of WFA (1  μM) may be imparting steric hindrance to the osteoblasts that may have attenuated proliferation at this concentration.

Taken together, our study provides convincing evidence for the candidature of WFA (10 mg kg−1 das−1) as a potential agent for the treatment of cartilage degenerative diseases like osteoarthritis.

Mean±SD WFA IC50 values were 3.7 µM±0.15 and 3.2 µM±0.21 for NHDF and HISMC, respectively.

STS cells were pretreated with a low dose of WFA (0.5 µM) for 4 h.

Similarly, low doses of WFA (0.5 µM) markedly inhibited STS cell colony formation capacity (Figure 1C).

Mice were assigned to two treatment groups: WFA (2 mg/kg/once daily) vs. DMSO (control group).

All STS cells evaluated demonstrated a capacity to grow in soft agar; this growth was abrogated after 24 h of WFA (0.5 µM) treatment (Figure 1D).

Similar to the previously described experimental approach utilized with STS cells, we used viable endothelial cells pretreated with short-term WFA (4 h) in modified Boyden chamber assays.