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Three small-molecule inhibitors known to suppress activity of kinases situated upstream of mitogen-activated kinases (MAPKs) inhibited the expression of IL-1β, IL-6, and CXCL1 when doxorubicin and vincristine were used singly or together, so specific kinase inhibitors may be useful in reducing inflammation in patients receiving chemotherapy.
Chemotherapeutic drugs were used, singly and then in increasingly lethal combinations to try to destroy all abnormal cells.
Multiple TB antigens were used singly and in combination for evaluation in the ALS assay.
When FNAB-Tgp and FNAB-Tgm were used singly they had a diagnostic performance comparable and not statistically different from that of FNAB-C.
Therefore, three drugs were used singly or in combination to test our hypothesis: the MAPK/BRAFV600E inhibitor, PLX4720 100 μM), PI3K/pAkt inhibitor, LY294002 (50 μM), and lexatumumab.
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These organisms may be used singly or in combination to obtain the desired flavour.
Pulleys are used singly or in combination to transmit energy and motion.
Unani medicines are used singly or are compounded with other substances to achieve synergistic, antagonistic, or detoxifying effects or simply as bases for effective ingestion and assimilation.
In addition, he said, companies looking to back up trading or clearing operations in Manhattan have several choices that can be used singly or in some combination.
6. Antique Scroll Fencing is available in 60-inch wide units that can be used singly or attached for longer fences.
A variety of protein biomarkers including C-reactive protein and pro-calcitonin (PCT) have been used singly and in combination to discriminate bacterial from viral infection24,25,26.
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