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were trail
verb
To follow behind (someone or something); to tail (someone or something).
synonyms
Exact(7)
Several lines responsive (IC50<0.05 μM) to AZD6244 or BEZ235 were TRAIL resistant (<10% dead cells at TRAIL 100 ng/ml), whereas a number of cell lines resistant to these inhibitors (IC50≥0.2 μM) showed good susceptibility to TRAIL (representative data in Figure 1a).
"These young women were trail blazers".
Treatment of MDM with individual cytokines IL-1β (50 ng/ml) or TNF-α (100 ng/ml) did not change membrane-bound or soluble TRAIL protein levels nor were TRAIL mRNA levels affected.
The majority of the cell lines were TRAIL resistant, resembling TRAIL sensitivity of primary cancer cells.
To gain further confidence that these results were TRAIL specific, we performed another screen where instead of TRAIL we used TNF α in combination with AZD5582.
However, recent observations demonstrating that a considerable portion of human cancers including those of the breast [ 27, 28] were TRAIL resistant undermined the potential application of TRAIL against cancer.
Similar(53)
They were trailing against Temple.
Ireland were trailing.
They were trailed throughout the trip.
The Cowboys were trailing by 24 late.
The Nets were trailing by 6.
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