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Lower doses (1.5 and 6 μ), when screened using MTT cell viability assays, had minimal effects on cell number, and were significantly less effective at inducing apoptosis in flow cytometry assays (data not shown).
In contrast, adenoviruses encoding angiostatin, endostatin, or neuropilin were significantly less effective.
Constructs containing the H1 promoter were significantly less effective in mice than those containing the U6 promoter, whereas both promoters functioned equally well in cultured cells.
Tremor varied significantly across stimulus conditions (P < 0.015), and stimulus trains with pauses were significantly less effective than stimulus trains without (P < 0.002).
In contrast, human I-1alpha, which lacks amino acids 83-134, and I-1 with C-terminal deletions were significantly less effective in promoting yeast growth under starvation conditions.
They found that N. sativa did induce bronchodilation within 30 min of administration but the magnitude was significantly less than observed with theophylline and that both agents were significantly less effective than the beta-2 agonist salbutamol.
Similar(41)
The decoctions did not interact with H2O2, but quenched DPPH although less effectively than vitamin C. In contrast, vitamin C was significantly less effective in protecting human gastric epithelial cells (AGS) from apoptosis induced by DPPH, peroxynitrite and H2O2 (P < 0.001).
Results suggest that duloxetine might be significantly less effective compared with venlafaxine, (in terms of treatment effects and number of response) with similar dropouts rates.
Thus, favorable intervention effects on self-rated health status may be significantly less effective for QOL among adolescents.
Combination therapy with 50 mg/kg ABZ and 2ME was significantly less effective in inducing apoptosis in tumor cells, compared with the effect of 50 mg/kg ABZ as a single agent (p < 0.05).
It was found to be significantly less effective compared with the reference treatment, both in the immediate and the sustained effect [ 15].
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