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A total of 37 transmembrane proteins were robustly affected, including 8 SNAREs (soluble N-ethylmaleimide-sensitive factor-activating protein receptors), and 7 lysosomal hydrolases were also depleted.
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In sum, the aging- and senescence-associated process of autophagy is robustly affected by lncRNAs.
Both proline degradation and biosynthesis are robustly affected by oncogenes or suppressor genes, and they can modulate intermediates involved in epigenetic regulation.
VAMP4 was the only R-SNARE to be robustly affected, but several Q-SNAREs were depleted, including syntaxins 16, 10, 8, 6, and 12, and Vti1 a and b.
In our model, parkin can only partially regulate the mitochondrial localization of Bax under normal conditions, where the N terminus is inaccessible, whereas the apoptotic conformation of Bax would be robustly affected by parkin under more pathologic conditions.
In contrast, proteins associated with ATM such as radiogenic phosphorylation of Chk2 and the expression of meiotic recombination 11(MRad50, Rand0 aNBS1BS1 were not robustly affected upon APPL protein silencing.
Then, following continued drug use, neurons located closer to the dorsolateral axis, such as nigrostriatal DA neurons, may be more robustly affected, leaving the machinery that encodes goal-directed behavior biased towards the drug of abuse.
The forces of reaction, however, were robustly intact.
All proteins were robustly expressed (Figure 1B, bottom).
Common genetic variants have been identified that robustly affect the level of circulating CRP [19] [21].
This paper studies the fundamental problems: whether an affine system affected by additive disturbances is robustly transferable from a source set (simplex) to a target set (polytope) and whether it is robustly stabilizable with its state constrained in a simplex.
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