The various change metrics were response variables in separate linear mixed models.
From the contour plots, general quadratic surface types of all response surface plots were response surface rising ridge.
Total extraction yield (Y), polyphenols content (PC) and total volatile compounds (TVC) were response variables in investigated experimental design.
Among time range examined, only leaf_6 h showed the up regulation which were response to (heat, chemical) stimulus and lignin biosynthesis.
Variables associated with survival and hospital discharge were: response time, witnessed arrest, bystander CPR, initial and average PETCO2, initial and final MAP, and ISS.
Water activity and the porosity of the bulk medium were response variables applied to a system for the biodegradation of hydrocarbons in the soil.
In the process, the liquid recovery yield (Y1) and the total content of DHA and EPA (Y2) were response variables, respectively.
Secondary end points were response rate (RR), progression-free survival (PFS) and VEGF-A level at baseline, mid-therapy and at the end of therapy.
The variables associated with restoration of spontaneous circulation (ROSC) were: response time, witnessed arrest, bystander CPR, average dose of epinephrine, ISS, initial and average PETCO2, and vasopressin therapy (Table 2).
The variables associated with survival and hospital discharge were: response time, witnessed arrest, bystander CPR, average dose of epinephrine, initial and average PETCO2, initial and final MAP, and ISS (Table 3).
The three GO terms enriched only in M4 were "response to inorganic substance" (GO: 0010035), "response to metal ion" (GO: 0010038), and "response to cadmium ion" (GO: 0046686) (Fig. 4c; Additional file 5: Table S3C).
