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The dorsal extrastriate cortex in the occipital lobe (V3A) and middle temporal cortex were reported to be relevant neural substrate for MA and MO based on structural MRI studies.
Through data querying for physiological mechanisms and genotype-association, 15 of these identified loci were reported to be relevant with those diseases, which indicate that our results are valuable for further disease-related studies.
MMP19 might be also involved in adhesion, detachment, and migration of thymocytes since it processes several ECM proteins including type IV collagen, nidogen-1, and laminin 5 γ2 that were reported to be relevant for the migration and development of thymocytes [16], [17], [68].
Some transcripts specifically modified by both EVs and tsRNAThr were reported to be relevant in host-parasite biology.
In addition, Ugt2b5 and Slc6a9 are also present in a blood signature for brain injury [ 42], while Dbh, Itgb1, Ltc4s, and Rhoa were reported to be relevant to mTBI [ 43].
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Recently, miRNAs are reported to be relevant to the self-renewal ability of cancer stem cells.
Chemosignals released by Ehrlich tumor-bearing mice have been reported to be relevant for the neutrophil activity changes induced by cohabitation.
Moreover, activation of the mTOR downstream target, p70S6K1, is reported to be relevant to p16 repression implying a potential role of p70S6K1 in aging and longevity regulation [31].
Some of the identified genes and pathways have been reported to be relevant to renal diseases.
Alternative lengthening of telomeres has generally not been reported to be relevant in melanoma.
MDH1 (malate dehydrogenase 1) in this pathway has been reported to be relevant with drug toxicity [ 64, 65].
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CEO of Professional Science Editing for Scientists @ prosciediting.com