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But they also noted that hypnotherapy helped "even those whose conditions were refractory to other forms of therapy".
Nine patients were refractory to the pharmacological treatments.
All patients were refractory to anti-TNFα treatments.
Her attacks were refractory to sumatriptan, very effective at sea level, but responded to oxygen.
All patients were refractory to conservative treatment for at least 6 months before the procedure.
In addition, both patients were refractory to traditional immunosuppressive therapy for their respective associated conditions.
Gα12 mutants deficient in PC1 binding were refractory to PC1 inhibition of Gα12-stimulated apoptosis.
All included cases were refractory to standard conservative treatments, such as medications and physical therapies for at least six weeks.
Diabetic patients whose foot ulcers were refractory to conventional therapy were treated with 12 successive cell-scaffold constructs on a weekly basis.
In our entire study cohort (n = 32), most of whom were refractory to chemotherapy, high hepatic tumour burden was associated with a poor prognosis.
Structures of individual domains have provided insights into their catalytic mechanisms, but with one exception, larger NRPS proteins were refractory to structure determination.
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