The form of polycystic (multiple-cyst) renal disease that allows survival into adult life is a familial condition, in which several members of the family have little trouble until middle life but then are progressively affected by kidney malfunction.
These results suggest that IRF3 and IRF7 can be activated by EBV but that IRF7 activity can be progressively affected after a prolonged stimulation with EBV.
We chose three neuroanatomical areas relevant to Parkinson's disease that according to the Braak hypothesis are progressively affected by alpha-synuclein pathology: medulla, midbrain and cingulate cortex (Braak et al., 2003).
In N-negative patients, DFS was progressively affected by a progressively more extended lymph nodes dissection: at a follow-up of 25 months (range 1 130 months), the DFS of patients with 0 6 and 7 15 resected lymph nodes was, respectively, 23 and 30 months, while it was not reached for patients with 16 22 and with more than 22 resected lymph nodes.
Ecologically, habitat fragmentation will have demographic effects as small populations are progressively more affected by demographic and environmental stochasticity greatly increasing their extinction probability (Lande 1993; Chevin et al. 2010; Leimu et al. 2010).
Since 2003, new social assistance schemes, and, more importantly, decentralization of routine treatment and care to community health stations, were progressively implemented in rural areas most affected by the HIV/AIDS epidemic.
As DNFB concentrations were increased, flagellar wave attenuation was gradually and progressively affected towards the more proximal regions and the mid-piece (Tombes et al. 1987).
From the mid-1950s onward the protectionist policies were progressively reversed.
While the spreading of TDP-43 pathology in our animal models is partly dependent on the distribution of transgene expression, TDP-43 pathology was found to progressively affect subcortical areas such as nucleus accumbens, the basolateral amygdala, and the caudate/putamen, areas also affected in FTLD-TDP brains4,55,56.
Affected families are progressively being moved to these sites so they can benefit from adequate relief services there and, little by little, rebuild their lives.
