Interestingly, CCL2 upregulation occurred at a time point where NFAT5 mRNA levels were not upregulated any longer compared to controls.
In contrast, TET1 and TET2, which are related to active DNA demethylation, were not upregulated in C.3 tumors.
Genes that were not upregulated more than twofold were used as negative examples.
This experiment was repeated at least 3 times Fig. 6 The levels of GAMYB transcript were not upregulated in Koshihikari.
These proteins were not upregulated under artemisinin treatment; rather, PFC0135C was markedly down regulated (0.28).
CCL25 transcripts levels were not upregulated in CCR9−/− large intestinal mucosa (Figure S2), probably due to the altered ratio of infiltrating cells to resident cells when compared to WT mucosa at the same time point (Figure S2).
Consistent with the global gene expression analysis, many genes known to be induced in early ectodermal differentiation of ESCs such as Isl1, Neurog3, Pax6 and Pcsk1 were not upregulated (fig. 2i).
While ATF4, GADD153 and to a lesser extent XBP-1 were upregulated in suspension, other genes commonly regulated during ER stress such as BiP/Grp78, PDI/Erp72, HSP47 were not upregulated.
There were 185 and 240 genes upregulated in wild type mice due to unloading, that were not upregulated in Nfkb1−/− and Bcl-3−/− mice, respectively, and so these genes were considered direct or indirect targets of p50 and Bcl-3.
Genes including the previously characterized NmsA, thought to encode an enzyme necessary for 2-methylnaphthalene metabolism, were not upregulated during growth of NaphS2 on naphthalene, nor were the corresponding protein products.
Gene expression analysis for 2'5'-oas, pkr and isg15, IFN-stimulated genes (ISGs) associated with an IFN-inducible antiviral response, revealed that the expression levels for these ISGs were not upregulated in H5N1 or H1N1 virus infected tissues.
