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High viral loads were not titrated beyond 750,000 viral copies/mL (log 5.88).
BUF 17 had a higher titre of antibodies against SAT 1 (160) compared to those against SAT 2 (80) and SAT 3 (20) (Table 2), while the sera of BUF 6 and BUF 10 were not titrated in the SPBE.
In 22 cases (18.8%), patients received a dose below the normal range, and in 16 cases (13.7%), drug doses were not titrated up to the maximum allowed dose according to the package insert.
By systematically varying these combinations, output gene expression levels were tunable over a 500-fold range (here TALEs were constitutively expressed from a common promoter, and therefore full TALE vs expression response curves were not reported since TALE concentrations were not titrated).
Similar(56)
Although treating physicians (cardiologists) were not blinded to values displayed on the BIS monitor, decisions to withdraw life support were never based on these parameters and the dosage of sedatives was not titrated based on BIS values.
The kiwi transcriptome library was not titrated.
Another limitation of the study was that nasal CPAP therapy was not titrated under polysomnographic monitoring but increased gradually to 10 cm/H2oror to the highest tolerated number.
We excluded RCTs with no description of or no difference in optimisation strategies between groups, as well as RCTs in which therapy was titrated to the same goal in both groups or was not titrated to predefined end points.
The inoculum was administered in three doses three days apart and although it was not titrated, it gave an optical density reading of >3.5 (upper limit of measurement) in the Bio-Rad TsSeE test.
On the contrary, the initiation of insulin in individuals with type 2 diabetes, even if it is not titrated to reduce blood glucose levels, was found to reduce β-cell stress and improve the conversion rate of IP [ 11, 12].
As ~50% of African people are SA, the burden of peripheral neuropathy can be very high if the doses of the drug are not titrated against the patient's capacity to remove the drug.
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