Sentence examples for were next validated from inspiring English sources

Candidate microglial gliomagens were prioritized to identify potential secreted or membrane-bound proteins, which were next validated by quantitative real-time polymerase chain reaction as well as by RNA fluorescence in situ hybridization following minocycline-mediated microglial inactivation in vivo.

The expression changes observed for S100A6, S100A10, S100A2 and S100A4 on array analysis were next validated in an independent series of experiments by RT PCR.

To ensure their clinical accuracy and completeness, the five health state descriptions were next validated by two consultant hematologists and two clinical nurse specialists who had treated patients with relapsed or refractory B-precursor ALL in the previous 36 months, and three patients receiving treatment for B-precursor ALL.

The biological importance of MSH2Y238 phosphorylation in the context of NPM-ALK pathobiology was next validated in ALK+ALCL cell lines, which express NPM-ALK at the steady state.

Histopathologic analysis of tissue sections was next performed to validate PET-derived results on PCT progression using an independent method.

DFT Raman simulations of a planar and twisted PBTTT model monomer system (BTTT-C2) are next performed to validate our proposed model and are shown in Figure 6 with their respective structures.

A mathematical model for the system is first presented and, next, validated with numerical and experimental data.

Based on the enrichment of low-differentiation cholangiocarcinoma cells by sphere formation and drug resistance, we considered that the proportion of cholangiocarcinoma stem-like cells had been increased, and we next validated the miR-200b/c expression levels of the parental and differentiated spheres and drug-resistant cells.

Having used both internal and external procedures to ensure that our predicted interactions were of high quality, we next validated a number of our interactions using a small scale E-MAP in the lab.

We next validated the results of the genes that were downregulated in Tax-expressing HeLa cells.

The genetic alterations that we identified were further validated through next-generation sequencing (NGS) and their association with a specific clinical stage was confirmed by comparison with 36 atypical hyperplasia (i.e. premalignant) tissues.