We think that the alternative motif shared with the Saudi lineage, 234-4216-6962, is stronger, as 1719 and 16148 transitions are more recurrent than 234, 4216 and 6962 [ 45].
This line of reasoning is supported by earlier reports that, among people with diabetes, episodes of MDD last longer and are more recurrent [ 32, 35].
There are more recurrent events than unique events (Fig. 1, Table 2), but unique events affect more of the genome (123 Mb, or 4.98%%) than recurrent events (51.5 Mb, or 2.08%%).
Moreover, these DNMs were more frequently recurrent than those identified in ID series.
SNRI-treated patients are more likely to be female, older, and were more complex (recurrent, with more severe and comorbid disorders) than SSRI-treated patients.
Lower limb injuries or disorders in the ankle or foot were mostly new (84 87%), whereas disorders of the back and the knee were more frequently recurrent conditions (Table 4).
In the elderly population, we found that women were more affected by recurrent injuries, which is consistent with older previously published results, but in contrast to a recently published study from a trauma center in Miami, which found more men among recurrently injured over 65 (Gubler et al. 1996; Allan et al. 2013).
SAEs were more frequent in recurrent EOC patients compared with advanced EOC patients (9/35 [25.7%] versus 7/92 [7.6%]), a difference which was statistically significant (P=0.006).
However, low PRDM2 mRNA levels were more frequently observed in recurrent tumors (p = 0.011) and BRC-resistant tumors (p = 0.037).
Further analysis of our data confirmed that low levels of PRDM2 were more frequently observed in recurrent tumors.
