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This latter mutant allowed us to evaluate the role of protein tagging in vivo under conditions that were more drastic than the point mutations affecting tag recognition described in previous studies.
Deglycosylation of TRAIL-R1 and TRAIL-R2 led to the diminished amounts of FADD and procaspase-8 at the TRAIL DISC, however, the effects were more drastic than upon deglycosylation of CD95 [24].
In contrast, the gene expression differences were more drastic between poly(A)+ and RiboZero RNA-seq, (Table 3).
Effects were more drastic with the minimal AbdAHD construct, which kept only eight interactions among the 31 positive TFs (compare Figure 3A,C, and Figure 3 figure supplement 2).
However, the effects were more drastic in Badami than in Pokkali, particularly during the early periods (9 h and 24 h) of exposure as observed from the ETR values presented as the percent of control in the inset (Additional file 8).
Similar(55)
This is more drastic".
Another change may have been more drastic.
There have also been more drastic approaches.
Elsewhere the vampirism was more drastic.
This is more drastic than simply being out of work.
With other models, the gap can be more drastic.
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