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We previously showed that spore germination was not required for internalization by non-phagocytic cells, and that spores of B. subtilis were internalized by host cells at a significantly lower frequency than that of B. anthracis spores [1], [6].
After 24 h incubation, TiO2 NPs were internalized by HCECs which were observed by TEM.
And then, the polymer-lipid hybrid NPs were internalized by the cells via endocytosis.
Penetrated tNG particles were internalized by skin cells in both epidermis and dermis.
Fluoresceinylated polyplexes (F-His-pLK or F-pDNA) were internalized by clathrin-dependent and -independent pathways.
Laser scanning confocal images clearly showed that folate conjugated DDSNs were internalized by A-549 cells.
TiO2 NPs were internalized by both cell lines after 24 h incubation which was observed by TEM.
Confocal images also revealed that PArg nanocapsules were internalized by the monolayer without evident signs of cytotoxicity.
Initially, the HPMA copolymers and HPMA copolymer drug conjugates were internalized by endocytosis and remained in endosomes/lysosomes.
The result indicates that very few NSs were internalized by the HeLa cells after incubating with the particles for 0.5 and 1.5 h.
In that study, EVs tagged by anti-CD9 and CD63 were internalized by macrophages via phagocytosis before they could promote cancer progression.
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