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Although heat-killed rough brucellae were internalized as efficiently as live bacteria, they did not induce macrophage cell death [9], [10], [11], [12], [13].
Apparently, these nonjunctional membrane domains consist of plasma membrane that is derived from both neighboring cells, and we have postulated that these areas might originate from plasma membrane regions that were located immediately adjacent to the GJ plaques, and were internalized as well.
And Henry Adams, who wrote within earshot of power his dyspeptic chronicle of failure and disappointment, suggested to Lowell how "his and our manic-depressive New England character" might be projected onto landscape and history, in the way that the region's extremes of bleakness and abundance were internalized as emotional poles.
The absolute intensity of the individual beads in the Alexa488/InlA experiments was used to ultimately determine the fraction of beads that were internalized as a function of time.
In addition, desmoplakin was detected as dot-like structures in the cytoplasm; disappeared from the plasma membrane of the BCl-2-expressing cells, indicating that desmosomal structures were internalized as large complexes upon loss of epithelial polarity.
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Notably, although high-molecular weight contaminants remain in our samples, they are unlikely to be an issue for internalization by electroporation as they will not be internalized as efficiently as our protein.
But those attitudes are internalized as well.
The racism around curry was internalized as well.
If a therapeutic protein binds to such a receptor, it will be internalized as well and located in sorting endosomes at a pH of ∼6 [ 2].
In conclusion, the results of our study show that fractions examined in vitro at the concentrations tested did not exert cytotoxic or clear genotoxic effect on pulmonary cells A549, although the particles have been internalized as clearly shown by TEM.
Although the focus of this analysis was on stigma in the community setting, stigma may occur in other settings such as health care facilities, may be reflected in laws and policies of governments and other institutions, may be internalized as well as external, and may overlap with additional stigma against marginalized groups such as sex workers or men who have sex with men.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com