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Consistent with this hypothesis, we found that the endogenous levels of RASSF9 mRNA were initially induced when keratinocytes were exposed to a calcium concentration of 2 mM (differentiation-inducing conditions) for 1 day, but were thereafter reduced as differentiation progressed (Figure S10).
Subcultures were initially induced under conditions of physiological osmolarity and normal human body core temperature (37°C).
A large number of overlapping modules were initially induced to capture the rich dynamics of the system.
Interestingly, Cluster VI comprised a set of genes that were initially induced and later repressed in K354 during stress (Additional file 4 and Additional file 5).
As shown in Figure 9, in drought conditions, the majority of the BrIPT and BrCKX genes were initially induced and upregulated before falling to basal levels during the time-course, despite the continuous application of the stressor.
The early/transient-response genes were repressed relative to untreated samples, the variable-response genes were initially induced and then repressed and the continuous/late-response genes were both repressed (set 5) and induced (set 6).
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Next, we hypothesized that resistance-related genes are initially induced through carboplatin treatment in A2780 tumors (initial response) and show higher basal expression level in vehicle-treated A2780cis tumors compared to vehicle-treated A2780 tumors (acquired resistance).
Cardiomyocyte hypertrophy was initially induced by the iso stimulation (100 nM) for 1.5 hours.
Anaesthesia was initially induced by intramuscular injections of ketamine (10 mg/kg) and midazolam (1 mg/kg) to allow preparation and handling of the animals and maintained with a mixture of ketamine (5 mg/kg) and midazolam (0.5 mg/kg).
To overcome the limited surface that fungi can inhabit at low water availability due to restrained growth, a MC optimal for growth should be initially induced, followed by a drying period to stimulate pigmentation.
In the case of convective mixing induced by QB, because forcing of QB is confined to the cloud base and is maintained, strong small eddies are initially induced around a thin unstable layer at the cloud base and spread to the middle and upper parts of the neutral layer.
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