Sentence examples for were initially activated from inspiring English sources

Importantly, this activity was captured dynamically, which identified pathways that were initially activated by a biochemical stimulus, and those pathways whose activity was altered subsequent to the initial stimulus.

The foreshocks were initially activated at the up-dip limit of the seismogenic zone ~30 km trenchward of the largest foreshock (M 7.3, two days before the mainshock).

Figure 3 shows that at p Ca = 4 steady-state ATP hydrolysis rates were initially activated up to 50% by 1 molecule of huC0C2 per 5 10 actin subunits in the thin filament (panel A).

To detect Acanthamoeba sp., the reaction tubes were initially activated at 95°C for 15 minutes followed by 40 cycles of amplification using denaturation at 94°C for 45 s.

PCR cycling conditions were initially activated at 95°C for 10 minutes followed by 43 cycles of denaturation at 95°C for 10 seconds, annealing and extension at 60°C for 20 seconds and data acquisition for 1 second at 72°C. Assay plates were run on the Roche LC480II and analysis performed by relative quantification.

In order to identify the population of Treg cells responsible for the conversion to IL-17-producing cells and the mechanisms behind this event, freshly isolated bead-enriched "whole" human Treg cells (CD4+CD25+) were initially activated in vitro in the presence of IL-1β, as previously reported [ 25, 26], and/or IL-2.

The resultant networks were further evaluated by the recall procedure, where a CA3 unit of the top layer (with overlap of 4) is initially activated and subsequent activity propagation in CA3 units according to recurrent connections is evaluated.

Ubiquitination involves a three-step enzymatic cascade, which is initially activated by ubiquitin-activating enzyme(E1).

Like ubiquitin NEDD8 is initially activated by its E1 activation enzyme APPBP1/UBA3 and transferred to the catalytic cysteine of the E2 (UBE2M or UBE2F in the case of CUL5) (Lammer et al, 1998; Liakopoulos et al, 1998; Osaka et al, 1998; Duda et al, 2008; Huang et al, 2009).

The activated pattern shows that autophagy is initially activated in the dendrites of the RGCs, but, thereafter autophagy is mainly activated in the cytoplasm of RGCs.

This, viewed in the context of our other findings, supports the hypothesis that T cells residing in an environment rich in tumour cells, are initially activated by tumour-associated antigens, but this activation leads to VEGFR-2 expression and finally to suppression, induced by the increased VEGF levels present within ascitic fluids.