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Most of the remaining players were inactive, on practice squads or on injured reserve.
Examples inhibited Pin1 activity with IC50 <100 nM, but were inactive on cells.
Although early analyses showed improvement in transplant rates in these groups, those assessments did not adjust for patients who were "inactive" on the waitlist because they had a temporary medical or social issue that blocked their eligibility for a transplant.
The compounds were inactive on NF54 (IC50 > 1000 ng/mL).
It is noted that in similar experimental conditions, ampicillin and chloramphenicol, used as standard drugs, were inactive on P. aeruginosa ATCC 27853, the data being in agreement with other experimental studies [38, 39].
While both PMSF and URB597 were inactive on [3H]-PEA hydrolysis by yeast homogenates, MAFP at 300 nM inhibited 50% of this activity, suggesting the involvement of a serine hydrolase (Figure 4C).
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It is currently unclear why the S. pombe demethylase complex is inactive on recombinant methylated histone H3, but one possibility is that an additional post-translational modification(s) is needed for the complex to effectively recognise its substrate.
However, except for a single copy in Ectocarpus, all other copies, both in this organism and all the metazoans, are inferred to be inactive on account of multiple stop codons disrupting one or more of the key functional ORFs.
The first enzyme not associated with Nit1C (1A21) was inactive on that substrate, while the next diverging ones (1A20, 1A22, 1A16, 1A17) were R-selective or not enantioselective (low bootstrap values do not support a robust branching order).
The synthesized D-seco vitamins, however, proved to be inactive on bone and intestine in vivo.
This season Beltran and most likely Reyes will be inactive on opening day.
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