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Those randomized to intensive policy were further randomized to sulfonylurea (n = 1,573) or insulin (n = 1,156), and a small number of overweight patients were randomized to metformin (n = 342).
Like for normalization, the data series incorporating uncertainty of gap-filling were further randomized by assigning a year from a uniformly distributed interval (1870, 2016) to each flood event, as in previous paragraph.
Interventions: Patients were randomized to full-Hammersmith and half-Hammersmith dosing regimens of aprotinin and were further randomized to hemofiltration or no hemofiltration.
Those assigned to the HFD were further randomized to receive rapamycin (2 mg/kg IP, MWF) or vehicle control (DMSO) during the last 4 weeks of the experiment.
Within each diet group, animals were further randomized to receive rapamycin (2 mg/kg) or DMSO (vehicle) given 3 times a week (e.g., Monday, Wednesday, Friday) via intraperitoneal injections during the last two weeks of the study.
Following surgery, rats from each group were further randomized to either: EE housing or standard laboratory housing (CON).
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The former arm was further randomized to CABG with traditional annuloplasty versus CABG with Coapsys.
At the one-year anniversary from enrollment, participating women could be further randomized into a CaD supplementation component.
From 6 to 12 months of age, infants are further randomized to a lipid-based nutritional supplement, with or without additional MMN.
To evaluate between-therapist differences in Physical Therapy, participants randomized to that intervention are further randomized to receive treatment by one of three physical therapists (two at the hospital Physical Therapy Clinic and one at a community therapy clinic).
The subset of women with HER-2-positive tumors (n = 232) was further randomized to either receive or not receive trastuzumab for 9 weeks together with the first three cycles of docetaxel or vinorelbine [ 14].
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