Subsequent replacement of the 7-hydroxyl with benzylamino groups was found tolerable.
If concurrent cediranib and chemotherapy were found to be tolerable at the stage I analysis, then the trial would be expanded and proceed to stage II.
Estimated risks under the likeliest environmental scenario were found to fall below the tolerable risk target of 10−4 infections per person per year.
The strategies of adoptive NK cell therapy were found to be feasible and tolerable without enhancing the risk of graft-versus-host disease or other adverse events, and anti-tumor efficacy has been reported in some studies [ 32– 32].
The outcomes of this SPC were found to be safe and tolerable with low incidences of AEs in a wide range of Chinese patients with uncontrolled BP on monotherapy.
This electrochemical detector is found to be tolerable to several electro-active chemical entities such as ascorbic acid, uric acid, dopamine, cysteine, nitrite, benzene, ammonium chloride, nitrate, citric acid, oxalic acid (negligible interferences), aromatic amine and sulfide.
In this paper, it is found that the tolerable maximum element size to achieve acceptable accuracy for soil shear strength is surprisingly small.
It is found that the tolerable flaw size for fracture in compression is in the millimeter range for both membrane systems at operating conditions in the range of practical interest.
While up to 2,000 mg per day was found to be tolerable, a plateau in pharmacodynamic effect advocated for 1,000 mg as the recommended monotherapy dose [ 39].
More recently, video assisted thoracoscopic surgery (VATS) has been found to be tolerable with similar rates of perioperative mortality and survival to open surgery in octogenarians [ 14– 14].
