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All patients were evaluable for assessment of clinical response, among which 1 obtained a 4.5-months partial response and 5 achieved stable disease.
A total of 66 courses were evaluable for assessment.
Seven of eight patients were evaluable for assessment of T cell response.
In total 50 patients received Seocalcitol treatment and were evaluable for assessment of safety.
All patients were evaluable for assessment of PK parameters after administration of the initial subcutaneous dose of PF-3512676.
In total, 50 patients were evaluable for assessment, with a complete record of clinical data and measurement of their EGFR status.
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Of 40 patients accrued to the study, 32 were evaluable for response assessment.
In 37/39 and 12/39 patients, respectively, thoracic and non-thoracic lesions were evaluable for response assessment.
In total, 14 out of 29 patients were evaluable for toxicity assessment after PK-guided dose escalation.
>> Of the forty six patients, who received first-line chemotherapy (median 6 cycles, range 1 12), 40 were evaluable for response assessment by RECIST criteria.
Twenty-nine oft of 43 patients were evaluable for PK assessments.
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