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Indeed, in order to exploit the vast array of opportunities that DESs offer to the biological industry, first, they must be established as safe mixtures.
Rehabilitation of the critically ill has been established as safe and feasible [ 6].
Regulatory agencies, such as the US Food and Drug Administration's Center for Drug Evaluation and Research, require that drugs be established as safe and effective prior to approval.
The use of azathioprine has been established as safe throughout pregnancy in a variety of clinical settings; transplant, inflammatory bowel and SLE literature [ 41, 42].
In summary, combination therapies have been established as safe and effective treatment options and their implementation into primary treatment centers in India and East Africa is ongoing.
For therapy, the physiologic compatibility of PLGA, PGA and PLA have been established as safe in humans; these materials have a history of over 30 years in various human clinical applications including drug delivery systems.
On the other hand, agents that inhibit the activity of the renin-angiotensin-aldosterone system (RAAS) system are being established as safe, effective and end organ protective in numerous clinical trials, resulting in their general acceptance as first-line treatment in most patients with stage 2 hypertension.
"We are nowhere near any part of Syria being established as a safe zone.
rTMS has been established as a safe and effective treatment for depression.
Sublingual immunotherapy (SLIT) is established as a safe and efficacious treatment for patients with type I respiratory allergies.
Mr. Spitz said his department did not impose water use restrictions in Suffolk County because the amount pumped from its reservoirs "does not exceed or even come near what is established as a safe yield".
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