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HSP90 and CHIP were earlier shown to stabilize WT p53 at higher temperature [24], [25].
HSP90 [24], CHIP [25] were earlier shown to suppress p53 aggregation and catalyze disaggregation at elevated temperatures.
Multiple non-receptor tyrosine kinases were earlier shown to increase AKT activity [43], [44], however, precise mechanism of AKT activation by any of the Tyr-modifications is not clear, nor is their role in initiation or progression of cancer.
HSP90 and CHIP were earlier shown to chaperone WT p53 [25], [25], the EMSA was repeated in the presence of HSP90 inhibitor geldanamycin and after utilizing bacterially expressed p53 that was passed through anti-CHIP and anti-HSP90 antibodies column (to terminate the role of any CHIP and HSP90 like homolog from bacterial system); similar results were obtained (Fig. 5c).
p53 cells were earlier shown to have better response to chemo- and radiotherapy.
CHIP and HSPs were earlier shown to interact with β-APP in a proteasome-dependent manner and influence Aβ metabolism (Kumar et al., 2007).
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Bert Cooper, a name partner, sniffs that the banker pitching Sterling Cooper — who was earlier shown furiously punching an adding machine — conducted only 20 minutes of analysis.
The 1,5-benzothiazepine-4-one scaffold was earlier shown to provide efficient protease inhibitors.
This method was earlier shown to be efficient in the characterization of particles supported onto porous materials [36 38].
Gallbladder disease and appendicitis are diagnoses in which it is earlier shown that US is of diagnostic value [15 17, 25].
The other gene (Affymetrix probe set ID, Os.7678.1.S1_at) has been earlier shown to be involved in JA biosynthesis in rice (Mei et al. 2006).
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