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As shown in Fig. 1C, levels of Fsp27 in WAT were dramatically elevated in ob/ob mice compared with that of wild type mice.
Following SEB challenge, the serum levels of all the cytokines/chemokines were dramatically elevated in SEB-treated HLA-DR3.IFN-γ+/+ HLA-DR3 mice.
Zip4 mRNA and protein were dramatically elevated in hepatocytes in the majority of human hepatocellular carcinomas relative to noncancerous surrounding tissues, as well as in hepatocytes in hepatocellular carcinomas occurring in farnesoid X receptor-knockout mice.
The α2 and β1 subtypes were dramatically elevated.
An investigation into the levels of IL-6 in terminally ill cachectic cancer patients found that IL-6 levels were dramatically elevated one week prior to death [ 59].
The α2 and β1 integrin subtypes were dramatically elevated, integrins α1 and α6 were lowered, whereas α5 was nearly lost in PC3res.
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For example, serum IL-6 levels are dramatically elevated in RA patients, and this elevation can be directly correlated with clinical and laboratory indices of disease activity, such as C-reactive protein (CRP) [ 17].
The protein expression of GFRα3 was dramatically elevated at 4 h and continually up to 10 h compared to normal control group (** P < 0.01, * P < 0.05).
The protein expression of Artn was dramatically elevated at 4, 6 and 8 h compared to normal control group (** P < 0.01, * P < 0.05).
Soluble IL-1Ra, an important member in IL-1 family of cytokines [29], was dramatically elevated in ARDS and septic patients [30, 31].
Within the critical period, c-Fos was dramatically elevated through 48 h after the lesion, while bFGF peaked later, on day 6.
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