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To date, all type II inhibitors were discovered by using structure-activity-guided optimization strategies.
New and improved catalyst compositions were discovered by using a total of seven generations each consisting of 92 potential catalysts.
For exploring possible diuresis mechanism of E. lathyris, in this study, a potential diuresis related target, urea transporter B (UT-B), and its potential ligands were discovered by using bioinformatics method of "Inverse Docking".
Artists like Justin Bieber and Karmin were discovered by using this forum.
Artists, like Justin Bieber and Austin Mahone were discovered by using this method and have gone onto to have great success.
Concise protein signatures of clinical endpoints were discovered by using statistical and computational analyses.
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A Russian drilling project designed to retrieve ice cores below the station was started in 1990, and a massive lake, spanning approximately 12,000 sq km (4,630 sq mi), was discovered by using satellite imagery and airborne ice-penetrating radar a few years later.
A novel class of selective SHP2 allosteric inhibitors was discovered by using the powerful 'SBP'ADMETMET' and 'CDOCKER' techniques.
In this study, a series of novel small molecular CypA inhibitors have been discovered by using structure-based virtual screening in conjunction with chemical synthesis and bioassay.
Firstly, the current proportional coefficients κ i are collected by each agent, the average value of which (kappa_p^{ast}) is discovered by using the distributed consensus method described in (12).
Very interesting patterns can often be discovered by using sound".
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