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We examined the localization of anillin and myosin II after Plk1 inhibition and found that both anillin and myosin II were delocalized from the contractile ring (Figure 4A, 4B).
The myosin II light (Rlc1) and heavy (Myo2) chains as well as the IQGAP protein Rng2 were delocalized from the cortex in interphase mid1Δ cells.
These results demonstrate that in DSas-4−/− cell lines, the centriole and PCM markers were delocalized from the poles and found dispersed in the cytoplasm (although still on the spindle for γ-tubulin).
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(D,E) In Cdc42loxP/loxP Fgfr3-iCre-ERT2 Cdc42loxP/loxP Fgfr3-iCre-ERT2 Cdc42loxP/loxP Fgfr3-iCre-ERT2ions and has a diffuse pattern.
Connected to these findings, our data show that aPKCλ/ι is delocalized from adherens junctions, suggesting that aPKCλ/ι activation, probably through Par6, is involved in mediating the effects of Cdc42 on structural maturation of the heads of supporting cells.
It can be seen in Fig. 6 that HOMO-1 and HOMO-2 are delocalized from the graphene matrix.
Within this PMI conceptual framework it can be shown that a system may be localized from the perspective of one observer and, nevertheless, may be delocalized from a different perspective.
Single and double SIM deletions were generated in the context of full length Pc2, or a truncated form (encoding amino-acids 2-531) that lacks the carboxyl-terminal 29 amino acids (the C-box), and is delocalized from polycomb bodies [38], [40].
The results contrasted with those obtained in cell culture in that the protein was delocalized from centromeres at the metaphase II/anaphase II transition.
Thus, it can be said that the population is delocalized from the fittest genotype for error rates sufficiently high but yet much smaller than that of completely random replication – evolutionary optimization breaks down.
In nearly all of the remaining germaria (70%, n = 83/119), Region 3 cysts were present but aPKC was delocalized from the cell surface of follicle cells surrounding these cysts.
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