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In order to identify the scale, the means of the item parameters were constrained to zero.
All six degrees of freedom were constrained to zero.
Subsequently we fitted the model in which only the parameters of interest were constrained to zero.
To simulate gene-deletion of a drug target, the fluxes through the corresponding catalyzed reactions were constrained to zero.
For gaps that have demand reactions in the model, the demand reactions were constrained to zero before running SMILEY.
In all three age groups, first a full MI baseline model (model 1) was fitted, where the covariate effects were constrained to zero.
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Models were constrained to three uncorrelated (|0.65|) variables to prevent overfitting to the dataset.
Several new introns were identified and their insertion loci were constrained to thirteen locations across the 16S rRNA gene.
To control the effect of the angle of approach for the cluster case, the angles were constrained to two distinct cases with 100 incoming molecules for each.
To ensure identification, the intercept is constrained to zero and the coefficient of one continuous regressor to one.
In addition, parameters are constrained to zero, if including the parameter does not improve the HQ criterion.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com