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Among the 14 (14.9 %) discordant cases, 9 were given a neurologic diagnosis by the consultant that was a different than the one given by the ED physician (Table 5) and all were concordant between the consultant and the final discharge diagnosis.
In total, 96 of 116 (83%) measurements were concordant between the two methods (12 hypomethylation and 84 hypermethylation events).
Estimates of pairwise population differentiation between 23 populations were concordant between microsatellite-derived data and AFLP analysis of the same samples (r = 0.71, p<0.00001, 425 individuals from 23 populations).
However, estimates of pairwise population differentiation were concordant between microsatellite-derived data and an earlier AFLP analysis of the same samples by Wee [26] (r = 0.71, n = 23, p<0.00001).
We defined sequencing accuracy (SA) as the percentage of the genotype calls that were concordant between 454 and Sanger vs. the sum of numbers of concordant and discordant calls; it can be also expressed as the symbols defined in Table S3.
As expected, the results were concordant between both approaches.
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Of the 94 cases in our study, 80 (85.1 %) had a neurologic diagnosis that was concordant between the ED physician and the consultant neurologist.
The vast majority of cases in our study (85.1 %) had a neurologic diagnosis that was concordant between the ED physician and the final diagnosis, which reflects the ability of emergency physicians to assess and diagnoses neurologic complaints.
The genes we observed whose expression is concordant between two discrete tissues within the same individual are involved in several cellular pathways and processes.
In our analysis, 86 cis-SNP genotypes were significantly associated with the expression of the 20 genes whose expression was concordant between two independent tissue types.
Although the genomic distribution of the predicted tRNAs was concordant between the strains we sequenced and MG1655 (Fig. S2), our strains were missing tRNAs that occurred in tandem at a single locus in the reference strain.
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