Sentence examples for were completely defective from inspiring English sources

Finally, we showed that double mutants between sid-1 and the yolk receptor were completely defective for inherited RNAi, even when SID-1 was expressed in the embryo.

Consistent with the result in Malt1 KO MEF cells, both CARMA3-deficient and BCL10-deficient cells were completely defective for NF-κB activation upon doxorubicin treatment.

Also, the data presented in this study in a similar shallow gradient showed that two alleles of che-1 were completely defective in chemotaxis to NaCl, even though che-1 appears not to be expressed in ADF, ASG or ASI [23].

All of the responses to IL-1 and IL-18 and the activation of NF-κB and MAP kinases were completely defective in cells from MyD88-deficient mice.

Importantly, the meiotic phenotype of dfp1-r35 suggests that disruption in prDSB formation is not its only defect, because rec12Δ mutants, which are completely defective for prDSB formation, nevertheless complete both meiotic divisions in with a normal timing and transcriptional program.

In Traf6 −/− cells, Q145N but not 2ED MAVS was completely defective in inducing IFNβ, but this defect was rescued by ectopic expression of WT but not C70A TRAF6.

"Maybe there's completely defective thinking [in the conventional view]," he says in the film.

IL-1R signaling in TRAF6-deficient fibroblasts is completely defective.

Each of these mutants was completely defective in NaCl chemotaxis (Fig. 3A).

Finally, the Tn10 double mutant was completely defective for the hairpin formation step, although the kinetics of the nicking step were relatively normal (Figure 4A, F).

Furthermore, in Anabaena, a patB deletion mutant was completely defective for diazotrophic growth, but in the wildtype, its expression was restricted to heterocysts [41].