Mean enrichment ratios for HNF4α at each promoter were calculated by using the five highest values located next to each other in each promoter, as we found that a positive signal typically expanded over five probes.
The mean cross-sectional cardiomyocyte diameters were calculated by measuring 100 cells with a centrally located nucleus per specimen.
Three out of the four expected selenium atoms in one molecule were located and initial phases were calculated by the program SOLVE [43].
Annual averages were calculated by adjusting for temporal variations using measurements obtained from a reference site located in urban background.
2014 were calculated by Simon Jackman.
These were calculated by bootstrapping, as follows.
P values were calculated by Student's t-test.
Gaps for 2012 and 2014 were calculated by Simon Jackman.
Relative species abundances were calculated by the MetaPhlAn pipeline37.
All hormonal parameters were calculated by the usual commercial methods.
