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All patients were assessable for toxicity and survival; 28 patients were assessable for response.
Among 30 patients enrolled, 25 were assessable for response rate (RR).
All patients with either PR or SD who were assessable for response received treatment until the time of documented disease progression.
All 11 patients in the previously untreated group and 12 of the 13 patients in the previously treated group were assessable for response, whereas all patients in both groups were assessable for toxicity.
Patients were assessable for response if they received one or more cycles of treatment; treatment response was evaluated every two cycles using appropriate radiographic imaging studies, complete history and physical examinations, and routine laboratory studies.
22 patients were assessable for response.
Similar(15)
No partial or complete response was observed on this study among the 14 patients who were assessable for responses.
Fourteen patients are assessable for response and all for toxicity.
Twenty-nine eligible patients started taking valproate and 18 received chemoimmunotherapy and are assessable for response.
In all, 50 patients were required in this phase II study, assuming that less than 20% of the patients entered would not be assessable for response.
Patients were considered to be assessable for response if they had evidence of early disease progression clinically or radiologically before two cycles, or if they had received a minimum of two cycles of treatment with at least one tumour measurement.
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CEO of Professional Science Editing for Scientists @ prosciediting.com