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Corresponding M-mode graphs were also acquired to demonstrate the capability to plot the pupillary diameter versus time (Fig. 2).

Images with excised rabbit and pig eyeball as well as mouse embryo were also acquired to demonstrate its imaging capability.

A T2-weighted axial scan and a coronal fluid-attenuated inversion recovery (FLAIR) scan were also acquired to exclude brain lesions in patients and controls.

T2-weighted images with 0.7-mm slices in axial, sagittal and coronal geometries (with respect to the magnet reference frame) were also acquired to perform relaxometry maps reference images by visualising the hypo-intensity corresponding to the labelled cells pellets.

Whole brain FLAIR images were also acquired to screen for clinical brain abnormalities.

Field maps were also acquired to correct for geometric distortions in EPI images caused by magnetic field inhomogeneities [37].

A high-resolution T1-weighted anatomic scan was also acquired to obtain a morphological reference (25 slices parallel to AC-PC with a resolution of 1×1×4 mm3, no gap).

Later sequences are also acquired to visualize the IVC optimally.

A corresponding spectrum without presaturation was also acquired to obtain a water signal reference.

To complement this data, inversion recovery (IR-) SPGR data is also acquired to correct for transmit magnetic field inhomogeneities [Deoni, 2011].

Aside from clinical purposes and evaluating inclusion and exclusion criteria, MRI-arthrographies are also acquired to obtain 3D shape parameters of the humerus, scapula and subacromial space with the use of MRI segmentation techniques (Amira 5.3, Visage Imaging Inc., San Diego, CA, USA).