Furthermore, patients are also excluded when they are already randomized in a currently ongoing randomized clinical trial (RCT) conducted at the Trauma Resuscitation Room of 1 of the participating Trauma Centers (AMC) (Netherlands Trial Registry no. NTR2607).
Since the intervention schools were already selected, a randomized, controlled trial could not be conducted.
Finally, in the study by Emilsson et al. [ 17], 54 adult ADHD patients who were already on medication were randomized to a CBT based group program or to treatment as usual.
The most common reason for positive responders not being randomized was that they were already active (baseline step count >70 000 steps/week).
The study, published in the Dec. 13 issue of the Journal of the American Medical Association, covered only people who were already ill with vascular disease, but the authors wrote that no randomized, controlled trials have shown a beneficial effect of B12 supplements in preventing vascular disease in healthy people, either.
However, several PHCs in Binh Thuan were already able to conduct FBCs, including some PHCs that were not randomized to receive RDTs (Table 1 and Figure 1).
Other possible exclusions included Soldiers who were being accelerated into a Company already randomized and recruited for participation in the Prevention of Low Back Pain in the Military trial or Soldiers who were being re-assigned to an occupational specialty other than a combat medic.
Of the nine centers that did not participate, two were not invited because they had already randomized almost all of their center cohorts; the other seven fourr of which were American Indian centers) declined to participate to minimize participant burden because they had elected to participate in other ancillary studies.
A 14-week LEAD-6 extension study was also completed, in which patients, already randomized to liraglutide, stayed on liraglutide, and those on exenatide switched to once-daily liraglutide (34).
New participants were assigned to the intervention group based on two specific covariates; sex and practice system, as well as previous assignments of participants already randomized.
