Sentence examples for were already activated from inspiring English sources
The [H]thymidine incorporation of unstimulated peripheral blood T cells from active SLE patients was significantly greater than that for patients with inactive SLE (P < 0.05) and normal control individuals(P < 0.005), indicating that peripheral blood T cells from active SLE patients were already activated in vivo.
Complex contrasts were generally masked inclusively making sure that in a complex contrast (e.g., A - B) only activation in those voxels gets displayed which were already activated (not deactivated) in the minuend (here: A).
ATM and CHK2 were already activated 20 min after the addition of MELK-T1, whereas the sustained p53 activation and p21 up-regulation appeared later.
It might be that in the apoptotic cells signalling pathways were already activated and the presence of Y-27632 could not have any effect.
It is tempting to speculate that antigen-presenting cells and helper T cells that were already activated in some patients contributed to the response seen in these patients.
Pathway analyses with DAVID confirmed that hematopoietic pathways were already activated in the CDH5+ fraction, a finding consistent with a hemogenic endothelium identity (Table S2).
Spontaneous PO is defined as the activity measured upon reaction with 3,4 dihydroxy-DL-phenylalanine (DOPA), and corresponds to the enzyme that is already activated in physiological conditions and total activity was the activity observed after in vitro activation of the enzyme, by preincubating the sample with bovine trypsin.
In summary, these results suggest that although the pathway is already activated in SCI, forced expression of active XBP1s locally into the spinal cord can still improve locomotor performance after experimental SCI.
This observation supports the hypothesis proposed by Kahl and Means that cancer cells containing a disruption in the cyclin D/cdk4 7 pRb regulatory pathway, may no longer require Ca2+/CaM to regulate the activation of this pathway because it is already activated or unnecessary for G1 progression in the tumour cells [ 38].
Our data show that elevated 5-HT2C receptors levels in the C2CR mice generate anxiety-like behaviour in the absence of exogenous ligand administration, suggesting that these receptors are already activated by the endogenous ligand and/or they are constitutively active.
The significantly increased percentage of ICOS+ cells and the significantly higher MFI with JTA009 in CD4+CD45RO+ T cells from patients with active SLE therefore indicates that these T cells are already activated in vivo.
