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Ten patients were accrued to the phase I portion, which utilized an accelerated titration design.
Phase I had 4 dose cohorts (.8, 1, 1.3, and 1.5 mg/m2) and 3 patients were accrued to each.
Very little, as a study by the department of economics at San Jose State University showed, suggesting that "special interests manipulated the levers of government to create a product whose costs far exceed its benefits" – and what benefits there were accrued to better-off travellers at the expense of the general population of taxpayers.
We designed a two-stage phase II study targeting a response rate of 30%<10%0% response would be uninteresting and ≥30% worthy of further study).Sixteen patients (10 male, 6 female) were accrued to the first stage of this study.
A total of 37 patients were accrued to the study from January 2004 to July 2005.
Between July 2010 and April 2011, twenty-nine patients were accrued to the COSMIC trial.
Similar(43)
It turned out that billions of dollars of benefits were accruing to farmers needing fewer inputs.
Once he had cemented his power, however, he managed the exchange ruthlessly, and his critics came to believe that the benefits of his work increasingly were accruing to him rather than to the institution.
If more than three complete responses were to occur, a further 20 patients would be accrued to the study (Simon's optimal two stage design).
Some £2.1bn has been accrued to pay staff their salaries, benefits and bonuses compared with £2.2bn a year ago at a time when revenue has dropped from £9bn to £6.3bn.
While stock is accrued to eventually be moved, say via sale, one of Twitter's co-founders has been extremely active in the market so far this year.
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