Sentence examples for were abrogated as from inspiring English sources

Consequently, the age-related patterns for C and SR flies under malnutrition characterized by a low number of changes due to the overruling stress-related expression appeared similar to ageing of SR flies under optimal food, where the age-associated changes were abrogated as a result of selection.

We report here that poxvirus protein F12 that has been implicated in intracellular enveloped virus (IEV) morphogenesis, and in particular IEV movement along microtubules [ 11- 13], is a derived DNA polymerase in which both the polymerase and the exonuclease activities apparently were abrogated as a result of mutational replacement of catalytic amino acid residues.

Thus, expression of Txnrd1 and Txnrd2 is abrogated as early as in neuronal progenitor cells [18] or early postnatal neurons [30].

Patient and animals studies show that disease severity is abrogated as SMN levels increase.

The observation that VEGF does not inhibit apoptosis if ceramide elevation is not suppressed (as upon exogenous ceramide addition), nor do anti-angiogenics sensitize if ceramide function is abrogated (as by treatment with anti-ceramide antibody), implies a fundamental role for a ceramide rheostat in radiation-induced endothelial apoptosis.

Under conditions of hypoxia, however, the interaction between HIF α and vHL is abrogated; as a consequence, HIF α becomes stabilized, leading to dimerization.

However, Ost2p/DAD-1 is also inactivated [ 39, 40] and the initial glycosylation of clusterin (and other glycoproteins) is abrogated as the structural integrity of the oligosaccharyltransferase is compromised [ 41].

While, the FST protein level increases when ER and ERR β interactions are abrogated as a result of 24-h E2 treatment, BCAS2 regulation is unique, as the maintenance of BCAS2 transcripts at the basal level requires the binding of ERs and ERR β.

By contrast, MAVS cleavage, as well as PARP processing, were abrogated in cells undergoing apoptosis in the presence of the caspase inhibitor (Additional file 3A).

The beneficial effects were mediated by macrophages as they were abrogated by transient macrophage depletion [280].

The cleavage of CTF1 was required for these functions, as they were abrogated by expression of the uncleavable CTF1 mutant.