"People like to hang tags on things but don't go labelling us a dirty side.
But Mara Clarke, the Director of the Abortion Support Network, believes there is still a long way to go, labelling the current laws "barbaric".
Only GO labels with a weight greater than 30% were considered as representative for the family.
Nearly half of the GO labels have <10 annotations in both species.
The distributions of GO labels with different numbers of annotations in yeast and human are shown in Figure 1.
GO annotation at the family level was obtained by listing the GO labels for all the genes that belong to a particular family.
A weight, equal to the percentage of genes carrying a particular label was assigned to all the GO labels in the family.
However, DCA also suffers from overfitting for sparsely annotated labels when predicting GO labels for a larger human interactome, if we want to train label-wise classifiers for all labels.
While extracting the GO labels we considered only the annotations with confidence score 5. We then filtered out all the GO terms associated with less than 20 and more than 100 proteins (473 GO terms).
Our GO (Ashburner et al., 2000) results take into account partial matches based on the deep hierarchy of the GO labels according to the methods of (Deng et al., 2003, 2004) and appear in the Supplementary Material.
