Sentence examples for well-established significance from inspiring English sources

Orthogonal polynomials have well-established significance in mathematical physics and numerical analysis (see e.g., [7]).

Despite the well-established ecological significance of photoperiodic diapause, the molecular basis of this crucial adaptation remains largely unresolved.

For the predictive values, the CI of the difference was not readily computable by well-established methods, but significance tests were carried out for these comparisons.

In the light of well established significance of CDKI proteins within the cell and in the development of pharmacological CDK inhibitors, it becomes essential to have facile methods of identifying these proteins.

There is debate regarding the clinical significance of well-established racial differences in HbA1c.

As mentioned in the introduction, there is well-established evidence supporting the clinical significance of RDI and its impact on survival in patients with aggressive non-Hodgkin's lymphoma or early stage breast cancer [ 1– 6].

This study investigated the significance of different well-established psychometric indicators of creativity for real-life creative outcomes.

This model connects dominant signal transduction pathways with cell-type origin, and further resolves the biological and clinical significance of the well-established markers ER and HER-2.

Usage significance is measured according to Component Rank, a well-established metric in the literature, which ranks software artifacts according to their usage significance.

The classification system considered the nature of an agent (well-established cause of encephalitis or not) and etiologic significance of a given positive laboratory test result.

Additionally, the prognostic significance of carcinoembryonic antigen (CEA), a well-established prognostic factor for colorectal cancer, was also analyzed to verify the reliability of this cohort of colorectal cancer patients.