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However, Gemox regimen is a well-established regimen since Sharma's study.
In metastatic colorectal cancer, 2-weekly irinotecan and infusional FU has been extensively investigated and is a well-established regimen based on its favourable efficacy and toxicity profile (Douillard et al, 2000; Tournigand et al, 2004).
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The combination of procarbazine, lomustine, and vincristine (PCV) is a well-established chemotherapy regimen in glioma treatment, as is temozolomide.
Only few evidences in the literature support the notion of adding a specific PPARγ agonist to well-established chemotherapeutic regimens for the treatment of PPARG-positive CRCs [30].
We have selected a regimen of 4 × 5 GY, a well-established palliative radiation regimen that can be safely applied to metastatic lesions in the lung, bone, and soft tissue [ 48].
"It replaces a safe and effective well-established screening tool and regimen that has prevented cervical cancer successfully in the US with a new tool and regimen not proven to work in a large US population," state the groups who oppose the test in a letter to FDA Commissioner Dr. Margaret Hamburg, according to the Associated Press.
8 Accordingly, we reasoned that a well-established non-myeloablative conditioning regimen 9, 10 typically reserved for high-risk, medically fragile patients that uses FLU and low-dose TBI, in combination with cyclosporine (CSP) and mycophenolate mofetil (MMF), could also be attempted in FA patients to facilitate engraftment without excessive toxicity.
We studied the role of THA and TKA patients' preoperative pain and functional characteristics in discharge from 2 orthopedic departments with well-established fast-track recovery regimens (Husted et al. 2010).
Despite the wide use of etoposide, there is a well-established correlation between chemotherapeutic regimens that include the drug and the development of therapy-related acute myeloid leukemias (t-AMLs) that feature rearrangements in the MLL (mixed lineage leukemia) gene at chromosomal band 11q23.
33, 34 However, due to no chance for endocrine therapy, 12 chemocycles of AC-T regimen was well-established for decreasing the risk of breast cancer recurrence, 17 implying that long-term persistent infusion of taxane/anthracycline-involved regimen was optimal for subpopulations with TN breast cancer.
Because of years of collaborative studies on these rare tumors, there is a well-established tumor-specific systemic therapy regimen for each histologic type.
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