Sentence examples for well-established master from inspiring English sources

Myc and NF-κB are well-established master regulators of initiation of transcriptional programs, but when deregulated, they function as oncogenic drivers in B cell lymphomas.

PGC1α is a well-established master regulator of mitochondrial metabolism [ 1] and has previously been reported to play a protective role against a variety of neurodegenerative conditions [ 23, 24].

It is well-established that TFs are the master regulators of embryonic development, as well as adult homeostasis, and that they are regulated by cell signalling pathways via transient protein interactions and modifications [ 27, 28].

While admitting that the notion of machines rising up against their masters is a well-established sci-fi device, Mr. Moore sees this new breed of enemy as a more ambiguous adversary, whose existence raises intriguing and complex questions.

Meanwhile, masters swimming was now well-established in North America and van Rysel began badgering the Amateur Swimming Association to introduce five-year age groups for over-25s.

Professional sports are well-established in Minneapolis.

Nonetheless, well-established instruments in the field such as large-scale comprehensive master plans are increasingly questioned.

To this aim we took advantage of the methodology of the well-established delitto perfetto approach for in vivo mutagenesis using oligonucleotides [ 40] starting with the master reporter strain yLFM-ICORE [ 41].

Making Arrangements: Classes Across the Country BOTANIC gardens generally offer basic flower-arranging classes and workshops, and well-established schools, like the Flower School New York and Rittners School of Floral Design in Boston, have more elaborate programs featuring introductory, intermediate and master classes.

Kazuo Ishiguro is the master of small things beautifully described, and in Never Let Me Go he takes a well-established archetype - a boarding school in the English countryside - and slowly subverts it.

"There are well-established areas with successful markets, but they still have to reinvent themselves," said Mr. Macsuga, noting that market masters are turning to extensive e-mailing, opening earlier in the year and closing later.