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However, no other therapies, including pharmacological treatment, can be considered to have well-established effectiveness in reducing tinnitus symptoms and the related quality of life [ 7- 9].
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The case for using subgroups based on biological-clinical and socio-demographic variables to address heterogeneity is well-established in effectiveness research, with the main issues being the statistical and clinical/policy significance of such analyses.
Despite well-established cost effectiveness of formal care services in high-income countries [ 46, 47] and enormous burden suffered by informal caregivers in LMICs, many LMICs continue to persist with informal caregiving as their paradigm for caring dependent older people.
We present the evaluation criteria of the effectiveness of psychological treatments developed by the American Association of Psychology for the evaluation of the Treatments with Empirical Support, distinguishing between: well-established well (effective) treatments, probably effective treatments and experimental treatments.
Modal-based damage detection techniques are well-established methods, whose effectiveness for Level 1 (existence) and Level 2 (location) damage detection is demonstrated by several studies.
Decision Analytic Models (DAMs) are one type of tool and are well-established in Cost Effectiveness Analysis (CEA) [ 7] as part of Health Technology Assessment [ 7- 10].
Despite the well-established antipyretic effects of oral and rectal acetaminophen, controversy regarding the comparative antipyretic effectiveness of the two types of acetaminophen preparations is yet unresolved.
Subjective evaluation of excitability and ranking of video segments demonstrate a higher correlation with the proposed measure compared to well-established techniques indicating the effectiveness of the overall approach.
And there is well-established precedent for the effectiveness of a genuine apology both personally and professionally.
Mortality is a well-established and commonly used effectiveness indicator that objectively captures the most serious adverse outcome.
For glaucomas that are refractory to medical and incisional surgical therapies, TCP is a well-established procedure and the effectiveness of the treatment on IOP reduction has been shown in various studies [ 6– 10].
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