In summary, we examined a number of well-established variables associated with Mtb infection and disease, and found that a risk score consisting of factors associated with transmission of Mtb did not distinguish PTST- individuals from those who eventually convert their TST or were TST positive at baseline.
The use of arterial homografts in clinical practice is becoming increasingly common, yet there is an urgent need to address one of the most well-established problems associated with their use: the loss of integrity of the endothelium following cryopreservation.
The predictive models, as expected, contained some of the well-established markers associated with each disease.
In this contribution we have shown that for the melanoma and prostate cancer datasets studied, the quantitative changes of Information Theory measures, Normalized Shannon Entropy, Jensen Shannon divergence and the novel Statistical Complexity quantifiers defined here are in high correlation with gene expression changes of well-established biomarkers associated to cancer progression.
Among the most well-established infections associated with a purported increased risk of autism is congenital rubella infection (89, 90).
There are well-established risks associated with delaying ART initiation in pregnancy, in terms of vertical transmission of HIV [ 10] as well as maternal morbidity and mortality [ 33].
Another well-established event associated with HCD is the increased inflammatory (e.g., TNF-α) signaling, which is also known to favor tumorigenesis (Park et al., 2010a).
Owing to the well-established risk associated with hypertension (HTN), the prevalence of HTN presents significant threats to public health in the USA and throughout the world.
Well-established genes associated with cellular senescence were identified from the literature, yielding a list of approximately 86 genes (Table S3).
These changes may reflect a partial mesenchymal to epithelial transition (MET) that is a reversal of epithelial to mesenchymal transition (EMT) a well-established pathway associated with development and carcinogenesis.
With regard to the gastric mucosa, aberrant DNA methylation is reportedly induced by Helicobacter pylori (19) and Epstein Barr (EB) virus infection (20), which are well-established factors associated with human gastric carcinogenesis.
