Aimed at 13C metabolic magnetic resonance imaging (MRI) and spectroscopy (MRS) applications, we demonstrate that dynamic nuclear polarization (DNP) may be combined with optimal control 2D spatial selection to simultaneously obtain high sensitivity and well-defined spatial restriction.
To gain more insight into the impact of nutrient availability on the adaptive transcriptional response towards hypoxia, we quantified the expression of the HIF-1α regulating PHD1 3 in heart, liver and skeletal muscle in young and old rats undergoing a well-defined protocol of caloric restriction.
The use of a well-defined algorithm including a restriction of the cannula size used for arterial cannulation decreased the number of ischemic complications when compared with two preceding studies of the same group in which a consistent rate of 10% ischemic complications was reported.
Driven by product quality, tool conservation and governmental restrictions a well-defined air filter is necessary for laser processes.
The molecular switches which arise from feedback loops within these circuits give rise to a well-defined sequence of successive gene restrictions corresponding to a controlled differentiation cascade in response to environmental stimuli.
Differentiation of the AFMS from anterior cancer is established by noting the midline location, well-defined margins, lack of true diffusion restriction (absence of high SI on b ≥1000 mm²/s EPI) and a benign progressive type 1 enhancement pattern at DCE (Fig. 3) [25, 30].
In particular, the model we have presented shows that the molecular switches which arise from feedback loops within core transcriptional circuitry naturally give rise to a well-defined sequence of successive irreversible gene restrictions which correspond to a controlled differentiation cascade in response to environmental stimulus.
We hypothesized that the restriction to a smaller well-defined sample would reduce heterogeneity and improve the power of detecting linkage.
"There is an absence of a well-defined vision, so they use words like 'religious restrictions,' " said Ibrahim el-Houdaiby, a researcher of Islamic movements and a former member of the Brotherhood.
One of the main issues with RESTful interfaces is that they lack a well-defined standard description language because of their own architectural restrictions.
