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The HADS has been used extensively, and is perceived as performing well when studying aspects of disease and quality of life in clinical as well as general populations [ 16].
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This relationship held as well when study completers only were evaluated.
While the impact of survey modality on responses has been well documented when studying topics of sensitive nature, such as HIV [29], the topic has not been rigorously studies when evaluating SRHS.
The discrepancy may be explained by photoreduction of the heme-iron to Fe2+ in the crystal by the X-ray radiation, resulting in a preference for ligation by methionine; beamline photoreduction is a well-known issue when studying hemoproteins and can result in conformational changes as well as changes in coordination state.
This works well in most cases when studying professional phagocytes, but it does not give any information about the ability to internalize per se.
Such limitations are well recognized by researchers when studying subjects who are at liberty to use a given product as part of their usual daily routine.
The modest within-group changes seen in our study suggest that these indices may not be particularly useful when studying well-controlled noninsulin-treated patients.
When studying well-characterized proteins as we have done here, episodes of functional change can be identified by piecing together several lines of evidence.
The US is our top choice when studying abroad as well, with nearly 9,000 of our citizens studying at American universities.
These can be particularly important when studying health and well-being.
When studying the professional well-being of health care providers, the current paper's first author [ 38] underscored the strong association between relevant training opportunities and a sense of confidence and competence in practice; this applies to a clinician's level of comfort in addressing sexual topics when assessing older patients.
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