While the challenges associated with cloud monitoring are well understood, the designs and patterns which attempt to overcome the challenges are not well examined.
38 This concept is well understood in design and production of wooden furniture, which ranges from unique craft made objects to those manufactured to precise and reproducible specifications.
Good design requires that these interactions be well understood and properly designed for the purposes of the information system in question.
Although the concept of marginally coupled designs is well understood, the results on design construction are scarce.
Although the principles of solar concentration are well understood, many practical design, operation, control issues require further understanding and research.
The behavior of these types of TLDs is not well understood, and a design procedure for this type of TLD is unavailable.
However, the structural behaviour of unlined and lined stud wall frames is not well understood and adequate design rules are not available.
In summary, it is well understood that model design is an iterative procedure, and while our logical analysis of numerical results suggested the step-wise addition or elimination of new features, there is no mathematical proof that the model ensemble is truly unique.
Despite the availability of crystal structures and the observation that mutations near the active site can alter the ratio of α-glycosidic bonds synthesized (Hellmuth et al. 2008), the reaction specificity of GH70 is not well understood, limiting the design of GH70 variants capable of synthesizing predefined α-glucan polymers.
The group sequential design has been well understood and widely applied in designs of late phase clinical trial to enable potentially early stopping for efficacy or futility.
The comorbidity of these conditions is well documented, but is less well understood, with few interventions designed to prevent or reduce the related consequences.
