In addition to its well recognized role in reverse cholesterol transport, HDL-C/apoA-I has been recently demonstrated to exert its effects on aortic endothelial cells by modulating expression of activin-like kinase receptors (ALK 1 and ALK2, thereby regulating BMP4 signaling [18].
HLA class I plays a well recognized role in tumor recognition and rejection but important roles for class II have also been indicated in recent years.
Answers were classified as correct when they contained exclusively food items whit a well recognized role as a vehicle for the pathogen under analysis.
In inflorescence, a well recognized role is played by miR156-miR172 regulation: miR156 decreases during inflorescence development while miR172 increases (Figs. 9A and 9B).
Preconditioning and postconditioning are the well described mechanisms that explain the protective myocardial effect of specific drugs in order to prevent the occurrence and/or to reduce the size of a necrotic post-ischemic myocardial area [ 1]: they play a well recognized role in the "protective effect" of the halogenated anaesthetics.
Moreover, the well recognized role that integrins (cell-ECM receptors) play in helping to generate isometric tension and Fn matrix assembly [ 51, 61], suggests that integrin-mediated signalling factors, like ILK, may provide a possible mechano-chemical pathway linking isometric tension with changes in the β-catenin and Fn levels.
We decided to utilise, during the learning period of developing the statistical methods, only data of individuals with pulmonary function tests (PFT) in the dataset, as PFT's play an important and well recognized role in the clinical assessment of CF [ 15].
4– 8 However, although the effects of RT in improving muscle strength and function are well recognized, its role in managing cardiometabolic risk factors has only lately attracted attention of scientific community.
Recent studies have recognized roles for 2-oxoglutarate dependent dioxygenases in histone and nucleic acid demethylation, as well as in signaling protein hydroxylation [19].
