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Income inequality is a well recognized problem.
Overweight and obesity have become a well recognized problem in many Western countries since the 1950s [ 1], mostly as a consequence of improved living conditions.
Chemical stress is a major and well recognized problem in modern bioprocessing due to toxic substrates and desirable or undesirable toxic metabolites [ 33].
In addition, it is also important to remember that test parameters are population specific and it is a well recognized problem that diagnostic test can have specificity problems when applied in an African context [ 42].
Nevertheless, this type of surgery reflects the surgery performed in most randomized trials studying adjuvant treatment in early stage ovarian cancer [ 17], while suboptimal surgical staging is a well recognized problem in early ovarian cancer [ 24, 25].
The rate of inconsistently protected sexual relationships during travel was however lower than expected ClinicalTrials.gov: NCT01056536 Among the risks frequently encountered by travelers abroad, sexually transmitted infections (STIs) such as HIV, hepatitis B, herpes simplex, syphilis or urethritis are a well recognized problem [ 1- 3].
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Obesity and related cardiovascular and metabolic conditions are well recognized problems for Australian Aboriginal and Torres Strait Islander peoples.
Other well recognized problems include oedema and renal insufficiency; however, the development of cyclooxygenase inhibitors (coxibs) has highlighted additional cardiovascular risks associated with these agents.
In addition, some well recognized problems of economical saccharification such as unproductive binding of cellulases, which reduces the hydrolysis rate and prevents recycling of enzymes, could be partially overcome by omitting CBMs.
The scarcity of medical research and its poor implications in health policy and evidence-based decision making are in fact well recognized problems in most developing countries including Iraq [ 3, 5, 17].
The use of this system is associated with some well recognized problems, mainly related to the issue that null mutants are heterozygous for URA3 and the Ura3 gene product can become limiting in vivo affecting virulence (Brand et al., 2004).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com