Sentence examples for well recapitulated from inspiring English sources

Therefore, the growth and survival advantages provided by the microenvironment, and CAM-DR are not well recapitulated in this model.

This is possibly due to the tumor heterogeneity that characterizes patients' tumors, which was here well recapitulated by the use of PDX models (Fig.  1d).

All of these complex mechanisms are noted in patients after prolonged treatment with erlotinib, but only few of these are well recapitulated using the standard cell line models, which tend to favor the gatekeeper mutation mechanism (even MET amplification is very rare in vitro).

Using a mouse model of breast cancer recurrence [ 5], well recapitulating the course of the human disease, we could confirm in vivo the relevance of STAT3 pathway in the occurrence of BC relapse following surgery.

However, the coding sequence of targeted endogenous genes was disrupted or the expression pattern of inserted exogenous genes could not well recapitulate the endogenous ones as insertion occurred within either the exon or cis-regulatory elements of targeted genes.

Despite being trained on exome data, the classifiers performed extremely well and recapitulated the results seen in the cross-validation experiments (Fig. 2).

Another optimality criterion for a novel de novo assembled transcriptome is how well it recapitulates previously determined sequences for the target species, and how well it represents sequences from related organisms.

For example, it is possible to utilize the high-level GO 'slim' functional terms, and then clusters can be evaluated in how well they recapitulate these terms, using sensitivity and positive predictive value measures, as introduced in an influential quantitative assessment of how well clustering approaches can uncover known protein complexes (Brohée and van Helden, 2006).

Herein we will examine what is known about the intestinal features of BE and how well it recapitulates the intestinal epithelium, including stem identity and function.

Determining activated GPCR states will often be more challenging then inactivate states, and the ability to use one active structure as a model for others, as well as recapitulating the activated function in the ligands, would have wide impact.

However, most TDP-43-based animal models fail to show characteristic TDP-43 containing cytosolic aggregates, raising questions as to how well they recapitulate key events of human disease.