Some tumours showed a diffuse decrease in Axin expression, others had both preserved and reduced expression in cell colonies, and others showed highly preserved expression.
Because our results demonstrate that TLR5 expression is well preserved in innate immune cells and various tissues from aged mice and that FlaB-dependent cytokines are significantly induced in aged macrophages, we determined whether FlaB enhances the innate immune responses through TLR5 activation in aged mice.
In addition, module preservation statistics allow a more quantitative view of how well preserved or divergent changes in gene expression are among species in broad-scale comparative transcriptomic studies such as ours.
Traditional multiplexed gene expression methods require well preserved, intact RNA.
The strength of correlation was similar between synchronous and metachronous metastases, which suggested that expression levels were well preserved, even in relapse, for long time after primary tumor resection.
The overlying retinal layers look well preserved.
Based on these results, we hypothesize that unlike other TLR pathways, the TLR5 expression and signaling pathway may be well preserved in the innate immune systems during aging.
These results suggest that quantal release in the two mutant mice with decreased expression of VAChT in the brain was well preserved at the NMJ.
We found that the expression of TLR5, but not TLR4, was well preserved in the aged tissues, similar to the young tissues.
Two novel orthotopic models of human PMP were established in mice, in which macroscopic growth pattern, the specific histopathologic subtype and immunohistochemical expression pattern of the implanted material were well preserved.
One month later, all retrieved implants released hARSA at rates similar to unencapsulated cells and contained well preserved myoblasts, demonstrating that encapsulation maintains differentiation of C2C12 cells, stable transgene expression and long-term cell viability in vivo.
